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  • 2024: 2023 Top Downloaded Papers, Light: Science & Applications. [Yogeshwar Nath Mishra, Peng Wang], Florian J. Bauer, Yide Zhang, Dag Hanstorp, Stefan Will, Lihong V. Wang, "Single-pulse real-time billion-frames-per-second planar imaging of ultrafast nanoparticle-laser dynamics and temperature in flames."

  • 2024: Outstanding Paper in 2023, Light: Science & Applications. Jongbeom Kim, Gyuwon Kim, Lei Li, Pengfei Zhang, Jin Young Kim, Yeonggeun Kim, Hyung Ham Kim, Lihong V. Wang, Seungchul Lee, Chulhong Kim, "Deep learning acceleration of multiscale superresolution localization photoacoustic imaging."

  • 2024: Best Paper Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Yide Zhang, Peng Hu, Lei Li, Rui Cao, Anjul Khadria, Konstantin Maslov, Xin Tong, Yushun Zeng, Laiming Jiang, Qifa Zhou, Lihong V. Wang, "Ultrafast single-shot 3D photoacoustic tomography in vivo using a single-element detector."

  • 2023: Hitachi High-Tech Best Presentation Award, High-Speed Biomedical Imaging and Spectroscopy Conference, Photonics West, SPIE, San Francisco, California. Yide Zhang, Binglin Shen, Tong Wu, Jerry Zhao, Joseph C. Jing, Peng Wang, Kanomi Sasaki-Capela, William G. Dunphy, David Garrett, Konstantin Maslov, Weiwei Wang, and Lihong V. Wang, "Ultrafast phase imaging of propagating current flows in myelinated axons and electromagnetic pulses in dielectrics."

  • 2023: Best Paper Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Yang Zhang, Joshua Olick-Gibson, Anjul Khadria, Lihong V. Wang, "Photoacoustic vector tomography for deep hemodynamic imaging."

  • 2022: Our publication, [Cao, R.; Zhao, J.]; Li, L.; Du, L.; Zhang, Y.; Luo, Y.; Jiang, L.; Davis, S.; Zhou, Q.; de la Zerda, A.; Wang, L. V.; "Optical-resolution photoacoustic microscopy with a needle-shaped beam," Nature Photonics (2022), has been highlighted in Nature. Read the article "Sharp laser beam reveals internal organs in stunning 3D" here.

  • 2022: Our publication, [Na, S; Russin, J. J.; Lin, L; Yuan, X]; Hu, P; Jann, K. B.; Yan, L; Maslov, K; Shi, J; Wang, D. J.; Liu, C. Y.; Wang, L. V.; "Massively parallel functional photoacoustic computed tomography of the human brain," Nature Biomedical Engineering (2021), has been featured in Nature Biomedical Engineering New & Views. Read the article "Real-time tomography of the human brain" here.

  • 2022:Best Paper Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Rui Cao, Scott Nelson, Samuel Davis, Yu Liang, Yilin Luo, Yide Zhang, Brooke Crawford, and Lihong V. Wang, "Label-free ultraviolet photoacoustic histology via deep learning for rapid intraoperative diagnosis of bone cancer."

  • 2022:Best Paper Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Shuai Na, Yang Zhang, and Lihong V. Wang, "Cross-ray ultrasound photoacoustic computed tomography of brain function."

  • 2021: Our publication, [Li, L; Li, Y]; Zhang, Y; Wang, L. V.; "Snapshot photoacoustic topography through an ergodic relay of optical absorption in vivo," Nature Protocols (2021), has been chosen to be featured on the homepage:
PATER featured on Nature Protocols homepage


  • 2021: Lei Li was elected as a 2021 TED Fellow. Visit the Caltech news report here.

  • 2021: Best Paper Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Shuai Na, Jonathan Russin, Li Lin, Xiaoyun Yuan, Peng Hu, Kay Jann, Lirong Yan, Konstantin Maslov, Junhui Shi, Danny Wang, Charles Liu, and Lihong V. Wang, "Mapping human brain function with massively parallel high-speed three-dimensional photoacoustic computed tomography."

  • 2021: Best Poster Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Li Lin, Xin Tong, Peng Hu, Marta Invernizzi, Lily Lai, and Lihong V. Wang, "Clinical photoacoustic computed tomography of breast cancer treated with neoadjuvant chemotherapy."

  • 2020: Lihong Wang was elected Fellow of the National Academy of Inventors (NAI).

  • 2020: 2019 Top Downloaded Paper, Light: Science & Applications. J. Y. Liang, L. R. Zhu, and L. V. Wang, "Single-shot real-time femtosecond imaging of temporal focusing."

  • 2020: Best Paper Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Lei Li, Zhiguang Wu, Yiran Yang, Peng Hu, Wei Gao, and Lihong V. Wang, "Photoacoustic computed tomography guided microrobots for targeted navigation in intestines in vivo."

  • 2019: Lihong Wang was elected Fellow of the American Association for the Advancement of Science (AAAS). "For pioneering 3D photoacoustic microscopy, functional photoacoustic computed tomography, and world's fastest camera (compressed ultrafast photography)."

  • 2019: Lihong Wang was elected Fellow of the International Academy of Medical and Biological Engineering (IAMBE).

  • 2019: Best Paper Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Yang Li, Terence T. W. Wong, Junhui Shi, Hsun-Chia Hsu, and Lihong V. Wang, "Multifocal photoacoustic microscopy through an ergodic relay."

  • 2019: Best Paper Award, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California. Terence T. W. Wong, Ruiying Zhang, Hsun-Chia Hsu, Konstantin I. Maslov, Junhui Shi, Ruimin Chen, Kirk Shung, Qifa Zhou, and Lihong V. Wang, "Whole-organ atlas imaged by label-free high-resolution photoacoustic microscopy assisted by a microtome."

  • 2018: Lihong Wang was invited to deliver the NIH/NIBIB Plenary Lecture, Annual Conference of BMES, Atlanta, GA.

  • 2018: Lihong Wang received an NIH/NCI Outstanding Investigator Award, NIH, Bethesda, MD.

  • 2018: Michael S. Feld Biophotonics Award. Congratulations to Dr. Lihong Wang who was selected as the recipient of the 2018 Michael S. Feld Biophotonics Award. The award, estabilished in 2012, honors Prof. Michael Feld for his fundamental contributions to applications of photonics technologies to solving biomedical problems.

  • 2018: National Academy of Engineering Elects 83 Members and 16 Foreign Members. The National Academy of Engineering (NAE) has elected 83 new members and 16 foreign members, announced NAE President C. D. (Dan) Mote, Jr., today. This brings the total U.S. membership to 2,293 and the number of foreign members to 262. Congratulations to Dr. Lihong Wang.

  • 2018: Opto-Acoustic Imaging Leader Seno Medical Instruments Announces Recipient of Its 8th Annual Best Paper Award during the SPIE Annual Conference. Congratulations to our lab members Lei Li, Liren Zhu, Cheng Ma, Li Lin, et al. for winning the 8th annual best paper award during the annual SPIE Photonics West conference with their work "Imaging Small-animal Whole-body Dynamics by Single-impulse Panoramic Photoacoustic Computed Tomography."

  • 2017: Shining Future of Biomedical Optics. Lihong V. Wang summarizes his tenure as Editor-in-Chief of the Journal of Biomedical Optics and introduces his successor, Brian Pogue, who will assume the role in January 2018.

  • 2017: Behind the Paper: Single-impulse Panoramic Photoacoustic Computed Tomography of Small-animal Whole-body Dynamics at High Spatiotemporal Resolution. Our lab members Lei Li and Liren Zhu discuss the motivation and development of our new photoacoustic computed tomography system which was recently published in Nature Biomedical Engineering.

  • 2016: Dr. Lihong Wang will present "Redefining the spatiotemporal limits of optical imaging" in the upcoming 2016 Gordon Research Conference on Image Science on June 7, 2016. See the flyer of the conference:
Advertisement flyer for Dr. Lihong Wang's presentation in the 2016 Gordon Research Conference on Image Science


  • 2015: Our paper "Optical-resolution photoacoustic microscopy for in vivo imaging of single capillaries" is one of the most highly cited articles in Optics Letters.

  • 2014: Dr. Lihong Wang will present "Photoacoustic tomography and wavefront engineering: ultrasonically beating optical diffusion and diffraction" in the upcoming Symposium on Physics and Medicine on February 26 and 27th, 2015.

  • 2013: Lihong Wang, the Gene K. Beare Distinguished Professor of Biomedical Engineering and a research member of the Siteman Cancer Center at Barnes-Jewish Hospital and Washington University School of Medicine, has received a 2013 Transformative Research Award from the National Institutes of Health (NIH). He was one of only 10 recipients of the award, given to scientists proposing highly innovative approaches to major contemporary challenges in biomedical research. The award promotes interdisciplinary approaches by investigators who propose research that has the potential to create or overturn fundamental paradigms. 
    The goal of the five-year, $3.5 million grant is to translate this technology, called single-cell label-free photoacoustic microscopy (PAM), immediately into the clinic for cancer screening, detection, prognosis and monitoring.
    https://news.wustl.edu/news/Pages/25917.aspx

  • 2013: Lihong Wang, the Gene K. Beare Distinguished Professor of Biomedical Engineering at Washington University in St. Louis, has received a three-year, $300,000 grant from the National Science Foundation (NSF) to study oxygen consumption rates of individual cells using photoacoustic microscopy, a novel imaging technology he developed that uses light and sound to measure change.
    https://news.wustl.edu/news/Pages/25138.aspx

  • 2012: Lihong Wang, PhD, has received a National Institutes of Health (NIH) Director's Pioneer Award to explore novel imaging techniques using light that promise significant improvements in biomedical imaging and light therapy.
    One of only 11 recipients of the highly competitive award, Dr. Wang was selected from among 600 applicants. The award supports individual scientists of exceptional creativity who propose pioneering and possibly transforming approaches to major challenges in biomedical and behavioral research, according to the NIH.
    The award will provide Wang with a total budget of $3.8 million over five years.
    http://www.nih.gov/news/health/sep2012/od-13.htm
    http://www.siteman.wustl.edu/ContentPage.aspx?id=6354

    https://source.wustl.edu/2012/09/wang-receives-38-million-nih-directors-pioneer-award/

  • 2012: Dr. Lihong Wang will be giving the following plenary lectures:

    1. SPIE Photonics Europe, 16 - 19 April 2012, The Square Conference Ctr., Brussels, Belgium
    2. Biomedical Optics (BIOMED), 28 April - 2 May 2012, Miami, Florida, United States
    3. ISBI 2012, 2 - 5 May, Barcelona, Spain

  • 2011: Our recent paper is about to be published on-line at Angewandte Chemie as a "Hot Paper":
    [Grigory S. Filonov, Arie Krumholz], Jun Xia, Junjie Yao, Lihong V. Wang*, Vladislav V. Verkhusha*, "Deep-tissue photoacoustic tomography of a genetically encoded near-infrared fluorescent probe," Angewandte Chemie International Edition
    http://onlinelibrary.wiley.com/doi/10.1002/anie.201107026/full

  • 2011: Junjie Yao's recent paper, "Label-free oxygen-metabolic photoacoustic microscopy in vivo,"  is highlighted in SPIE Professional Magazine:
    http://spie.org/x57337.xml

  • 2011: Dr. Lihong Wang was awarded the C. E. K. Mees Medal for "seminal contributions to photoacoustic tomography and Monte Carlo modeling of photon transport in biological tissues and for leadership in the international biophotonics community." Announced at the OSA Congress on Optics in the Life Sciences, Monterey, CA on April 4, 2011 [Link]

  • 2011: The following paper has been identified as a "hot article" for Journal of Materials Chemistry and highlighted on their blog: [Link]
    Chulhong Kim, Hyon-Min Song, Xin Cai, Junjie Yao, Alexander Wei and Lihong V. Wang, "In vivo photoacoustic mapping of lymphatic systems with plasmon-resonant nanostars," Journal of Materials Chemistry, DOI:10.1039/C0JM04194G (Feb. 2011)

  • 2010: Best Poster Award to Song Hu, Gordon Conference on Lasers in Medicine and Biology, Plymouth, NH. Song Hu, Konstantin Maslov, Jeffrey M. Arbeit, Jin-Moo Lee, Lihong V. Wang, "Optical-Resolution Photoacoustic Microscopy for Biomedical Applications"
    http://www.grc.org/programs.aspx?year=2010&program=lasersmed

  • 2010: The following paper is highlighted in Science to Practice by Radiology:
    http://pubs.rsna.org/doi/full/10.1148/radiol.10091772
    Todd N. Erpelding, Chulhong Kim, Manojit Pramanik, Ladislav Jankovic, Konstantin Maslov, Zijian Guo, Julie A. Margenthaler, Michael D. Pashley, and Lihong V. Wang, "Sentinel Lymph Nodes in the Rat: Noninvasive Photoacoustic and US Imaging with a Clinical US System," Radiology 2010;256(1)  102–110 (July 2010)

  • 2010: A review paper by C. Kim, C. Favazza, and L. V. Wang has been featured on the cover of Chemical Reviews:
    C. Kim, C. Favazza and L. V. Wang, "In Vivo Photoacoustic Tomography of Chemicals: High-Resolution Functional and Molecular Optical Imaging at New Depths,"  Chemical Reviews, Vol. 110(5), pp. 2756-2782 (May 2010)
    http://pubs.acs.org/doi/abs/10.1021/cr900266s

A review paper by C. Kim, C. Favazza, and L. V. Wang has been featured on the cover of Chemical Reviews


  • 2010: Lihong Wang and Hsin-I Wu receive Goodman Book Writing Award (List of winners) from SPIE and OSA
    BELLINGHAM, Washington, and WASHINGTON, D.C., USA -- Lihong V. Wang and Hsin-I Wu are recipients of the 2010 Joseph W. Goodman Book Writing Award for their book Biomedical Optics: Principles and Imaging, the Optical Society (OSA) and SPIE have announced More>>

  • 2010: From the New Editor-in-Chief
    Lihong V. Wang
    J. Biomed. Opt. Vol. 15, 010101 (Feb. 18, 2010)
    Download the PDF (56 kB)

  • 2010: Highlights of 2009 by the journal of Physics in Medicine and Biology [Link]
    M. Pramanik, K. H. Song, M. Swierczewska, D. Green, B. Sitharaman, and L. V. Wang, "In vivo carbon nanotube-enhanced non-invasive photoacoustic mapping of the sentinel lymph node," Physics in Medicine and Biology, 54, 3291–3301 (May 2009)

  • 2010: Best Paper Award to Konstantin Maslov, Photons Plus Ultrasound Conference, Photonics West, SPIE, San Francisco, California
    Konstantin Maslov, Geng Ku, and Lihong V. Wang, "Photoacoustic microscopy with submicron resolution," Proc. SPIE, Vol. 7564, 75640W (2010); doi:10.1117/12.841919. [PDF]

  • 2009: Best Poster Award to Song Hu, Photons Plus Ultrasound Conference, Photonics West, SPIE
    Song Hu, Konstantin Maslov, Lihong V. Wang, "Monitoring the healing process of laser-induced microvascular lesions using optical-resolution photoacoustic microscopy," Proc. SPIE 7177, 71772I (2009). DOI: 10.1117/12.809327 [PDF]

  • 2009: SPIE announced the appointment of Lihong V. Wang of Washington University in St. Louis as editor of the Journal of Biomedical Optics (effective January 1, 2010). More>>

  • 2008: First-place Best Poster Award to A. Garcia-Uribe, K. C. Balareddy, J. Zou, K. K. Wang, L. V. Wang, "A novel micro optical sensor probe for early diagnosis of upper gastrointestinal (GI) cancers," pp. 910-913, 2008 IEEE Sensor Conference. DOI: 10.1109/ICSENS.2008.4716589.

  • 2006: Best Paper Award to Konstantin Maslov, Photons Plus Ultrasound Conference, Photonics West, SPIE. Konstantin Maslov, Hao Zhang, Mathangi Sivaramakrishnan, George Stoica, and Lihong V. Wang, "Technical considerations in quantitative blood oxygenation measurement using photoacoustic microscopy in small animals in vivo," Proc. SPIE 6086, 60860R, (2006). DOI: 10.1117/12.646265.

  • The following books were published:

    1. L.V. Wang, Photoacoustic Imaging and Spectroscopy (CRC, 2009)
Photoacoustic Imaging and Spectroscopy book
Purchase from Amazon.com

2. L. V. Wang and H.-i Wu, Biomedical Optics: Principles and Imaging (Wiley, 2007).
Biomedical Optics book

Homework solutions are available to course instructors. Course instructors who have adopted this book as a textbook may request a copy of the solutions manual from Wiley (http://www.wiley.com/WileyCDA/WileyTitle/productCd-0471743046.html).
Wiley FTP (ftp://ftp.wiley.com/public/sci_tech_med/biomedical_optics/)Download readme.
Download programs.
Purchase from Amazon.com.

3. V. V. Tuchin, L. V. Wang, and D. A. Zimnyakov, Optical Polarization in Biomedical Applications (Springer, Berlin Heidelberg, 2006).
Optical Polarization in Biomedical Applications book
Purchase from Amazon.com.